Figure 6From: Role of transcription factor Sp1 and CpG methylation on the regulation of the human podocalyxin gene promoterEffect of mutating the Sp1 recognition sites on the activity of podocalyxin promoter. Transient transfections were performed into HEK293 cells. Results represent mean ± SEM from four independent experiments performed in duplicates. Promoter activity of each transfection was expressed as a ratio of luciferase/renilla activities. Data are expressed as percent of the maximal activity of the -210 construct *p < 0.05 vs. non Sp1-site-mutated construct.Back to article page