Skip to main content

Table 1 Correlation and Monte Carlo data values

From: DNA deformability changes of single base pair mutants within CDE binding sites in S. Cerevisiae centromere DNA correlate with measured chromosomal loss rates and CDE binding site symmetries

UNSIGNED PD

Monte Carlo

Mutant Group

Data Points

R Value

Slope

Reg. P-Value

Prob.(Better R-Value)

Prob.(Steeper Slope)

CDE I Core

24

54.6

0.186

.0057

.016

.009

CDE III Core

21

54.7

0.427

.0103

.052

.044

CDE I & III

45

50.1

0.347

.0004

.003

.003

ALL

67

43.0

0.264

.0003

.020

.007

Non Core

22

11.3

0.018

.6100

.280

.460

SIGNED PD

  

CDE I Core

24

-30.1

-0.08

.152

.098

.050

CDE III Core

21

-68.0

-0.37

.0007

.059

.011

CDE I & III

45

-22.9

-0.11

.130

.228

.282

ALL

67

-30.1

-0.12

.013

.083

.065

Non Core

22

15.4

0.02

.493

.206

.194

  1. Results for plots of Loge (chromosome loss rate) vs UNSIGNED PD or SIGNED PD delta sums for various mutant groupings: CDEI Core = CDEI positions 1 thru 8; CDEIII Core = CDEIII positions 11 thru 17; Non Core = All other position mutants. The R-value is the signed correlation, the regression P-value is a statistical measure of the slope significance. The right 2 columns show the control P-value results from the Monte Carlo method (see text).
Back to article page

BMC Molecular Biology

ISSN: 1471-2199

Contact us