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Figure 4 | BMC Molecular Biology

Figure 4

From: DNA deformability changes of single base pair mutants within CDE binding sites in S. Cerevisiae centromere DNA correlate with measured chromosomal loss rates and CDE binding site symmetries

Figure 4

Histograms of Monte Carlo R-value distributions for CDEI & CDEIII sites as a result of randomizing the PD-scale. Histograms of the Monte Carlo distributions of R values are shown calculated from 105 randomizations of PD-scale values. In each histogram the actual value from the true PD-scale is marked by a triangle along the x-axis. Shaded dual tail areas correspond to probabilities of better correlations than the actual value reported in Table 1. The normal curve, superimposed on each of the histograms using the mean and standard deviation of the distribution, reveals the normal character of the CDEI distributions (A) & (C) and contrasts with the bimodal CDEIII distributions (B) & (D).

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BMC Molecular Biology

ISSN: 1471-2199

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