Skip to main content
Figure 1 | BMC Molecular Biology

Figure 1

From: Alternative first exon splicing regulates subcellular distribution of methionine sulfoxide reductases

Figure 1

Splice variants of mouse and human MsrA. (A) Schematic illustration of genomic structures of alternatively spliced MsrA forms in humans and mice. Translation initiation sites are indicated by arrows. Exons are shown by boxes and are numbered. The number of residues in each of the human and mouse forms is indicated on the right. (B) Alignment of mouse and human mitochondrial MsrAs (the a form in A) and MsrA(S)s (the b form in A). The mitochondrial signal peptide is indicated in italics. The catalytic cysteine in the GCFWG sequence and two cysteine residues in the last exon are highlighted. The arrow indicates the last amino acid residue of exon 1.

Back to article page