Figure 2From: Recognition and binding of mismatch repair proteins at an oncogenic hot spotComparison of binding avidity of G:T-containing oligomer by MMR proficient (HCT 116 + Ch. 3) and MMR deficient (HCT 116; hMLH1-/-) nuclear extracts. Equal aliquots of nuclear extracts from HCT 116 + Ch. 3 (lanes 1–3) or HCT 116 (lanes 4–5) were incubated with equal cpm of [32P]-G:T-oligo (69-mer) and 50X molar excess cold (unlabeled) oligo as indicated.Back to article page