Table 1 10 selected candidate housekeeping genes
From: Selection of reference genes for gene expression studies in human neutrophils by real-time PCR
Gene symbol | Gene Name | Accession Number | Function | Gene synonyms | |
|---|---|---|---|---|---|
| Â | Â | mRNA | genomic DNA | Â | Â |
ABL1 | Abelson murine leukemia viral oncogene homolog | NM_007313 | NT_035014 | Cytoplasmic and nuclear protein tyrosine kinase | ABL, JTK7, p150, c-ABL, v-abl |
ACTB | Beta-actin | NM_001101 | NT_007819 | Cytoskeletal structural protein | Â |
B2M | Bata-2-microglobulin | NM_004048 | NT_030828 | Cytoskeletal protein involved in cell locomotion | Â |
GAPD | Glyceraldehyde-3-phosphate dehydrogenase | NM_002046 | NT_009759 | Glycolytic enzyme | G3PD, GAPDH |
GNB2L1 | Guanine nucleotide binding protein, β-peptide 2-like 1 | NM_006098 | NT_077451 | Involved in binding and anchorage of protein kinase C | H12.3, RACK1, Gnb2-rs1 |
HPRT1 | Hypoxanthine phosphoribosyltransferase 1 | NM_000194 | NT_011786 | Constitutively expressed at low levels, involved in the metabolic salvage of purines in mammals. | HPRT, HGPRT |
PBGD | Porphobilinogen deaminase | NM_000190 | NT_033899 | Deficiency of porphobilinogen deaminase results in acute intermittent porphyria | HMBS, AIP, UPS |
RPL32 | Ribosomal protein L32 | NM_000994 | NT_005927 | Member of the 80 different ribosome proteins | Â |
TBP | TATA-binding protein | NM_003194 | NT_007583 | Involved in the activation of basal transcription from class II promoter | GTF2D, SCA17, TFIID, GTF2D1 |
TUBB | Beta-tubulin | NM_001069 | NT_034880 | Member of the tubulin family of structural proteins | Â |