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Table 1 Percentage of total luciferase activity per organ measured in the Brown Norway and Wag/Rij rats 2 days after intravenous administration of 3.109 iu of Ad.Adapt.luc virus. The luciferase activity is expressed in RLU / mg protein. Data are expressed as mean ± SD. Fresh organs were weighted and the mean value is expressed in grams / 100 grams body weight. The muscle mass was estimated from the human situation as 40% of total body mass. The bone marrow was previously measured.

From: Genetic heterogeneity in response to adenovirus gene therapy

Organs Weight (g / 100 g) Brown Norway (n = 14) Wag/Rij (n = 6)
Liver 3.4 97.91 ± 2.35 96.88 ± 4.76
Spleen 0.3 1.93 ± 2.05 1.99 ± 1.52
Heart 0.5 0.072 ± 0.04 0.06 ± 0.05
Lung 0.8 0.037 ± 0.04 0.04 ± 0.005
Kidney 1.1 0.001 ± 0.008 0.03 ± 0.02
Muscle 40 0.005 ± 0.06 0.89 ± 0.92
Brain 1 0.003 ± 0.006 Not done
Bone Marrow 1 0.028 ± 0.01 0.11 ± 0.23