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Table 6 Intracellular concentration (μM) of ApppN as a function of stress treatments, HNT2 genotype, and moderate overexpression of lysyl aminoacyl-tRNA synthetase

From: Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae

Relevant Genotype -his 1 M sorbitol 10 mM caffeine 2 mM CdCl2 46°C H2O YPD
HNT2 0.58 ± 0.36 1.19 ± 0.37 1.15 ± 0.12 1.12 ± 0.29 2.16 ± 0.10 0.54 ± 0.12 0.44 ± 0.09
HNT2 YEpKRS1 0.60 ± 0.51 0.84 ± 0.21 2.74 ± 1.37 1.14 ± 0.17 2.11 ± 0.25 0.49 ± 0.05 0.41 ± 0.13
hnt2Δ 10.7 ± 7.51 6.65 ± 0.82 12.5 ± 3.91 4.92 ± 2.67 44.2 ± 7.51 5.92 ± 1.66 5.97 ± 1.38
hnt2Δ YEpKRS1 19.0 ± 8.21 6.36 ± 2.10 3.84 ± 1.05 11.6 ± 4.36 40.6 ± 5.62 8.82 ± 3.57 1.40 ± 0.52