Control of dinucleoside polyphosphates by the FHIT-homologous HNT2 gene, adenine biosynthesis and heat shock in Saccharomyces cerevisiae

Table 2 Intracellular concentration (μM) of dinucleoside polyphosphates in segregants from three complete BY71 tetrads

Culture Time	24 hr		48 hr		72 hr
Nucleotide	ApppN	AppppN	ApppN	AppppN	ApppN	AppppN
Segregant							Relevant Genotype
1a	5.96	0.27	112	0.26	251	0.19	hnt2Δ ADE2
1b	14.2	0.11	42.7	0.12	101	0.16	hnt2Δ ade2
1c	1.44	0.16	2.86	0.09	2.50	0.09	HNT2 ade2
1d	0.26	0.04	1.07	0.38	0.60	0.16	HNT2 ADE2
2a	42.6	0.23	86.6	0.19	102	0.18	hnt2Δ ade2
2b	39.1	0.37	294	1.51	346	0.26	hnt2Δ ADE2
2c	0.29	0.06	0.40	0.05	0.36	0.05	HNT2 ade2
2d	2.59	0.17	0.86	0.21	0.57	0.07	HNT2 ADE2
4a	21.6	0.52	160	0.37	200	0.42	hnt2Δ ADE2
4b	0.51	0.09	0.24	0.002	0.09	0.001	HNT2 ADE2
4c	0.34	0.07	0.95	0.03	0.80	0.06	HNT2 ade2
4d	8.21	0.10	26.7	0.07	52.1	0.19	hnt2Δ ade2

ISSN: 1471-2199