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Figure 1 | BMC Molecular Biology

Figure 1

From: HIPK2 overexpression leads to stabilization of p53 protein and increased p53 transcriptional activity by decreasing Mdm2 protein levels

Figure 1

Activation of p53-mediated transcription by HIPK2 overexpression. 293 (A), HeLa (B) and Saos2 (C) cells were cotransfected with a p53-luciferase reporter construct and the indicated HIPK2 constructs or vector. Results represent the mean of three independent experiments. Bars, SD. (D) Western analysis of transient overexpression of Flag-tagged wildtype HIPK2 in HeLa cells (right lane) compared to vector-transfected control cells (left lane) with an anti-Flag antibody.

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BMC Molecular Biology

ISSN: 1471-2199

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