Figure 2From: Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic miceExample of LOH analysis. Blots of tumor and tail DNAs, digested with Pst I, were probed with a 32P labeled Pten probe. Two bands could be observed, representing wild type and mutant alleles, as indicated at the left. Genotypes of mice are shown at the top.Back to article page