Figure 2
From: Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice
Example of LOH analysis. Blots of tumor and tail DNAs, digested with Pst I, were probed with a 32P labeled Pten probe. Two bands could be observed, representing wild type and mutant alleles, as indicated at the left. Genotypes of mice are shown at the top.