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Figure 4 | BMC Molecular Biology

Figure 4

From: Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine

Figure 4

Enteroendocrine cell allocation is decreased in Gata6ΔIE and DKO mice. (A) Quantification of CHGA-positive cells in each group. Sections of ileum were stained for CHGA, and the number of positive cells/1000 epithelial cells was determined as described in Methods. (B) Chga and Neurog3 mRNA abundance in each group. Gata6Δ IE and DKO mice had generally lower numbers of CHGA-positive cells and Chga and Neurog3 mRNA abundances than Ctl mice, consistent with a decrease in enteroendocrine lineage allocation.

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BMC Molecular Biology

ISSN: 1471-2199

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