Figure 3From: Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestineCrypt cell proliferation is decreased in Gata6ΔIE mice. (A) Immunostaining in ileum for the proliferation markers Ki67 (top row) and BrdU (bottom row). (B) Quantification of Ki67- and BrdU-positive cells/crypt in each group. Cells were counted as described in Methods. Gata6Δ IE mice had significantly fewer Ki67- or BrdU-positive cells than each of the other three groups (P < 0.01 in each case), consistent with a decrease in crypt cell proliferation.Back to article page