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Figure 3 | BMC Molecular Biology

Figure 3

From: Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine

Figure 3

Crypt cell proliferation is decreased in Gata6ΔIE mice. (A) Immunostaining in ileum for the proliferation markers Ki67 (top row) and BrdU (bottom row). (B) Quantification of Ki67- and BrdU-positive cells/crypt in each group. Cells were counted as described in Methods. Gata6Δ IE mice had significantly fewer Ki67- or BrdU-positive cells than each of the other three groups (P < 0.01 in each case), consistent with a decrease in crypt cell proliferation.

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BMC Molecular Biology

ISSN: 1471-2199

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