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Figure 6 | BMC Molecular Biology

Figure 6

From: Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cells

Figure 6

Wnt4 overexpression in human papillary thyroid cancer cells inhibits cellular migration. Wound healing migration assay for BCPAP, BCPAP-pCEFL and BCPAP-Wnt4 was performed. The healing of the wounds by migrating cells was imaged at time 0 h, 4 h, 8 h and 12 h (upper panel). BCPAP-Wnt4 cells migrate significantly less than BCPAP and BCPAP-pCEFL cells. Wound closure is expressed as the percentage of the initial wound diameter at 0 h. Data are expressed as the mean ± SD (P < 0,01, right panel).

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