Figure 6From: Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cellsWnt4 overexpression in human papillary thyroid cancer cells inhibits cellular migration. Wound healing migration assay for BCPAP, BCPAP-pCEFL and BCPAP-Wnt4 was performed. The healing of the wounds by migrating cells was imaged at time 0 h, 4 h, 8 h and 12 h (upper panel). BCPAP-Wnt4 cells migrate significantly less than BCPAP and BCPAP-pCEFL cells. Wound closure is expressed as the percentage of the initial wound diameter at 0 h. Data are expressed as the mean ± SD (P < 0,01, right panel).Back to article page