Figure 1
Shapiro and Senapathy [[4]] scores for pseudo splice sites scoring higher than the lowest-scoring genuine APOB splice sites. The dotted lines show the scores of the genuine splice sites flanking exon 26. (A) Scores of 5′ splice sites (ordinate) plotted against position in exon 26 (abscissa). (B) Scores of 3′ splice sites (ordinate) plotted against position of the in exon 26 (abscissa). The arrow indicates the pseudo splice site that is used in the alternative splicing event identified in Figure 6. (C) Table of positions and Shapiro and Senapathy scores of pseudo 5′ splice sites in exon 26 scoring higher than the native 5′ splice site at position 7572. (D) Table of positions and Shapiro and Senapathy scores of pseudo 3′ splice sites in exon 26 scoring higher than the native 3′ splice site at position 1. The asterisk indicates the pseudo splice site that is used in the alternative splicing event identified in Figure 6.