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Table 4 Biological processes and pathways linked to experimentally defined and differentially expressed genes in TIA-depleted HeLa cells

From: Identification of a set of miRNAs differentially expressed in transiently TIA-depleted HeLa cells by genome-wide profiling

Categories enriched in

Description

Number of genes

Gene symbol

p-value

Up-regulated genes

 

GO term

 

GO:0070555

Response to interleukin-1

2

IL1R1, IRAK2

6.21E-04

GO:0045087

Innate immune response

2

IL1R1, IRAK2

6,88E-03

GO:0007165

Signal transduction

2

IL1R1, IRAK2

2,88E-02

KEGG term

 

Kegg:04080

Neuroactive ligand-receptor interaction

2

CNR1, F2RL2

6.88E-03

Kegg:04210

Apoptosis

2

IL1R1, IRAK2

1.43E-03

Down-regulated genes

 

GO term

 

GO:0032836

Glomerular basement membrane development

2

COL4A4, NID1

1.09E-02

KEGG term

 

Kegg:04144

Endocytosis

4

RAB22A, AP2B1, DAB2, PLD1

3.23E-02

Kegg:04142

Lysosome

3

CTSC, AP1S2, LAMP2

4.77E-02

  1. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) databases analysis were carried out using GeneCodis3 software.