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Figure 4 | BMC Molecular Biology

Figure 4

From: The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cells

Figure 4

Functional analysis of the MTG16 promoter by sequential 5'-deletion. The following 5'deleted reporter constructs were generated from the pGL3 -820-57 (-820) construct and examined after expression in erythroid HEL/TF-1, erythroid/megakaryocytic UT-7 and megakaryocytic MEG-01cells: pGL3 -668-57 (-668), pGL3 -512-57 (-512), pGL3 -359-57 (-359), pGL3 -339-57 (-339), pGL3 -299-57 (-299) and pGL3 -219-57 (-219). Promoterless pGL3/basic and the pGL3/SV40-promoter are used as negative and positive control, respectively. The luciferase activity was normalized against pGL3/SV40- promoter activity. Results are shown for 3 to 5 separate transfections; bars represent the mean and the error bars show SEM.

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