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Figure 4 | BMC Molecular Biology

Figure 4

From: Recombination phenotypes of the NCI-60 collection of human cancer cells

Figure 4

Clonal GCI assays. for each cell line analyzed, TK-10, K562, T-47D, A549, NCI-H23, EKVX and MCF7, clonal populations are on the far left of each panel with individual subclones derived from single cells in the clonal population on the right. Open star: 1 Mb resolution limit. Brackets: clusters missing in the subclones, yet present in the clonal population. Open triangles: clusters found in the subclones, yet missing in the clonal population. Arrows: minor intensity bands from sub-populations arising from mitotic recombination during early subclonal expansion. Low molecular weight dotted pattern: cluster fragments derived from site-specific fragility in the cluster broken during DNA processing.

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