Figure 6
From: Drosophila Ctf4 is essential for efficient DNA replication and normal cell cycle progression
Knockdown of CTF4 results in defects in ovary and early embryo development. Representative confocal micrographs of egg chamber ovarioles at stage 7 in CTF4 knockdown and wild-type controls showing apoptotic-like DNA condensation in CTF4 knockdown nurse cells (right panels). Representative confocal micrographs of DNA stained with DAPI in Drosophila early embryos from both CTF4 knockdown and wild-type controls (left panels). Mitotic bridging can be seen in the Ctf4 knockdown group but was absent from controls.