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Figure 3 | BMC Molecular Biology

Figure 3

From: Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells

Figure 3

Analysis of miRNA-mediated regulation of endogenous NTRK3 in neuroblastoma cells. A. Western blot analysis of NTRK3 levels in RA-differentiated cells transfected with mimics targeting FL-NTRK3; NTRK3 levels are reported relative to control cells. B. Analysis of ERK1/2 phosphorylation after acute stimulation of differentiated SH-SY5Y cells with NT3. Basal phosphorylation in unstimulated cells is also shown (-NT3). C. NTRK3 levels in undifferentiated cells transfected with mimics targeting TR-NTRK3. Data from four independent experiments are presented as means ± SE (*p < 0.05).

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