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Figure 5 | BMC Molecular Biology

Figure 5

From: Essential role for ALCAM gene silencing in megakaryocytic differentiation of K562 cells

Figure 5

ALCAM alters expression of PKC in K562 cells. A) Quantification of PKC mRNA level in K562-ALCAM (#1, #2) and K562 (#15) clones at steady-state (vehicle) and following treatment with 20 nM PMA for 48 h. B) Western blot analysis showing expression of the indicated proteins in control K562 clone #15 (lanes 1, 4), ALCAM-expressing clones #1(lane 2, 5) and #2 (lanes 3, 6) at steady-state (-) and following treatment with PMA (+). C) Quantification of PKCα and PKCδ activation.

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