Figure 3
From: High-resolution melting curve analysis for rapid detection of mutations in a Medaka TILLING library
ENU-induced mutations identified by TILLING in the Oryzias latipes atm gene (OlATM). (A) Genome organization and protein structure of the medaka atm gene. Conventions are as in Fig. 1. The FAT domain, PI3-kinase domain (kinase), and FATC domain are shown. High-resolution melting curves (B, D, F, H) and subtraction plots (C, E, G, I) of identified ENU-induced mutations in exons 1, 2, 9, and 57-58 of the atm gene are shown.