Figure 5

Summary of the results and definition of two domains in the structure of RAI1. By in silico analyses, several domains have been found for RAI1: a polyglutamine tract at the N-terminal of the protein (in blue), two polyserine domains (in yellow), a PHD domain at the C-terminal of RAI1 (in slanted lines) and two putative nuclear localization signals (in black). The schematic representation of all the mutants analyzed in this study is shown. An asterisk represents the missense mutations. Two defined domains are depicted.