Figure 1
From: Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes
The inhibitory effects of DMAT and TBBz on viability and proliferation of HeLa cells. Cells were grown in the presence of 1, 5 and 10 μM of DMAT (A, C) or 1, 5, 10 and 25 μM of TBBz (B, D). Cell viability was monitored by MTT test (A, B), and cell proliferation by 3H thymidine incorporation (C, D) 24 and 48 h later. Four independent experiments were performed, and all assays were repeated in octuplicate. Results are expressed as the percentage of control cell viability or proliferation and represent means ± S.D. *; P < 0.05 compared to the control.