Figure 2From: Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in miceRepresentative tumor histologies in Topors+/- mice. Representative sections of H&E-stained tissues are shown. A. Papillary Harderian gland tumor (×20). B. Thymic lymphoma (×10). C. Histiocytic sarcoma involving liver and bladder (x10). D. Bronchoalveolar adenocarcinoma of the lung (×10).Back to article page