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Figure 7 | BMC Molecular Biology

Figure 7

From: The transforming acidic coiled coil (TACC1) protein modulates the transcriptional activity of the nuclear receptors TR and RAR

Figure 7

Interaction with TACC1 changes TR intracellular localization. The GFP-TRα1 construct was transfected into non-targeting siRNA (A) or TACC1 siRNA (B) treated HEK-293F cells. The distribution of GFP-TRα1 was analysed by confocal microscopy. The cell nuclei were stained with DRAQ5 (red colour). Two representative pictures are shown for each condition. We never observed the GFP fluorescence in the cytoplasm of the control cells.

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