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Table 3 Immune-protective effects of recombinant cystatin

From: Preliminary molecular characterization of the human pathogen Angiostrongylus cantonensis

Group Number of mice Cystatin immunization Number of surviving mice (21 days) Average number of larvae recovered (x ± SD) Reduction in number of larvae
A 20 No (negative control) 8 27.7 ± 8.45 /
B 20 Yes 18 13.2 ± 4.52* 52.3%
  1. *Significantly different compared to control group (P < 0.01). After immunization, each mouse in two groups was challenged with 40 infective larvae (L3) of A. cantonensis. The challenge experiment and protection analysis were performed once. Each experimental group was composed of two parallel groups, each containing 10 mice.