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Table 1 cDNA clones predicted to encode protease family proteins

From: Preliminary molecular characterization of the human pathogen Angiostrongylus cantonensis

Clone No. N Homologous gene [organism] Protease family Functions
0009D10 1 Serine protease pcp-1 precursor 1 [C. elegans] Serine
Facilitates penetration and migration [3840]; Immune evasion [41, 43]; Lysosomal protection
0005E12 3 Cathepsin A
[Monodelphis domestica]
00012B11 1 Cysteine proteinase
[Haemonchus contortus]
0007D03 1 Cathepsin B-like cysteine protease 2 [Parelaphostrongylus tenuis]   
0014F02 2 Cathepsin B-like cysteine protease 1 [P. tenuis] Cysteine protease Degradation of hemoglobin and serum albumin [36]; Iron acquisition; Larva molting; Degradation of phagocytosed material; Immune evasion [44, 45]
0005F12 4 Cathepsin L 1
[Dictyocaulus viviparus]
00012F09 10 CathePsin Z family member (cpz-1) [C. elegans]   
15G12 1 Aspartyl protease family member (asp-1) [C. elegans]   [42]
0006G04 2 Aspartyl protease protein 6 [C. elegans] Aspartyl protease Digestion of hemoglobin serum protein [35, 37]; Intestinal digestion and tissue degradation; Initiates a catabolic pathway; Immune evasion [42]
00010A09 3 Aspartyl protease family member (asp-2) [C. elegans]   
16B10 14 Cathepsin D-like aspartic protease [Ancylostoma ceylanicum]   
  1. N indicates total number of cDNAs in the corresponding cDNA cluster.