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Figure 1 | BMC Molecular Biology

Figure 1

From: Loss of the insulator protein CTCF during nematode evolution

Figure 1

Conserved genomic organisation of invertebrate CTCFs. A, B, C: Genomic CTCF loci of vertebrates, Drosophila [19] and Trichinella, drawn to scale. Transcription start (arrow), transcription end (polyA), translation start (ATG) and stop (TAA, TAG, TGA), exons (box), introns (line), protein coding region (shaded), and zinc finger region (light green) are indicated. To illustrate the structure of vertebrate CTCFs, human CTCF is depicted (accession number NT_010498). D: Domain organisation of tsCTCF. â“…: Predicted Tyrosine phosphorylation site, polyQ: poly-Glutamine tract, S-rich: Serine-rich region, N-rich: Asparagine-rich region, RCC1: RCC1 chromatin binding motif, ZF: Zinc finger region. Predicted N-glycosylation, N-myristoylation and most phosphorylation sites are not shown.

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