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Figure 9 | BMC Molecular Biology

Figure 9

From: Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia

Figure 9

Time-dependent reduction in the levels of serum bilirubin and rHO-1 by siRNA in neonatal hyperbilirubinemia rats models. A and B: The inhibitory rate of siRNA-4 on HO-1 protein 48 hours after injection was 33%, after 72 hours, it was in a time-dependent decrease. No inhibitory effect of siRNA on HO-1 protein was found in NC group. C. Effect of 10 OD/20 g bw siRNA-4 on levels of bilirubin at different time points. *P < 0.05, compared with blank group; #P < 0.05, compared with NC group. Data represent the results from one of three independent experiments. Each group contained 4–6 mice.

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BMC Molecular Biology

ISSN: 1471-2199

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