Skip to main content
Figure 8 | BMC Molecular Biology

Figure 8

From: Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia

Figure 8

Dosage-dependent reduction in the levels of serum bilirubin and rHO-1 by siRNA-4 in neonatal hyperbilirubinemia rats models. A and B: The inhibitory effect of siRNA-4 on rHO-1 in liver increased concomitantly with increased injection doses. The inhibitory rates at 10 OD/20 g bw, 5 OD/20 g bw and 3 OD/20 g bw dosage were 42%, 30% and 10%, respectively. C. Effect of different dosages of siRNA-4 on the levels of bilirubin. *P < 0.05, compared with control group. Data represent the results from one of three independent experiments. Each group contained 4–6 mice.

Back to article page

BMC Molecular Biology

ISSN: 1471-2199

Contact us