Figure 4From: Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemiaEffect of hemin on rHO-1 protein. A. The effect of hemin at different concentrations on the level of HO-1 protein. BRL cells were treated with 1.5 μmol/L, 4.5 μmol/L and 15 μmol/L hemin to induce the HO-1 expression, result of Western Blot 18 hours after the treatment indicated that the level of HO-1 protein was in a hemin dose-dependent way to increase. B. The change of HO-1 protein level induced by 4.5 μmol/L hemin at different time points. Eighteen hours after treatment with hemin, the level of HO-1 protein reached its peak.Back to article page