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Figure 3 | BMC Molecular Biology

Figure 3

From: Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia

Figure 3

Dose- and time-dependent down-regulation of rHO-1 by siRNA. A and B. The dose-dependent inhibitory effect of siRNA (*P < 0.01, compared with untransfected controls). The doses of siRNA used in the experiments were 0 nmol/L, 1 nmol/L, 10 nmol/L and 50 nmol/L. C and D. Time-dependent inhibitory effect of siRNA. The time points were 15 hours, 24 hours and 48 hours at a siRNA dose of 10 nmol/L. The maximum inhibitory effect of siRNA-4 was observed at 24 hours. (*P < 0.01 or **P < 0.05). The results represent values derived from three independent experiments.

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BMC Molecular Biology

ISSN: 1471-2199

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