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Table 2 Predicted binding sites for HNF4α in ABC genes.

From: Expression of HNF4alpha in the human and rat choroid plexus – Implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier

Gene name

Accession number

bp relative to transcription start site

Score core/matrix

 

Human

    

ABCB4

NM_000443.3

-6274 to -6252

V$zemlin13_11045

1.000/0.896

  

-4680 to -4658

V$HNF4_01

1.000/0.990

   

V$zemlin13_1104

1.000/0.997

  

-4063 to -4041

V$HNF4_01

1.000/0.954

   

V$zemlin13_11045

1.000/0.958

ABCC1

NM_004996.3

-1756 to -1734

V$HNF4_01

0.915/0.925

  

-5266 to -5244

V$HNF4_01

1.000/0.944

   

V$zemlin13_11045

1.000/0.969

Rat

    

ABCB4

NM_012690.1

-4584 to -4562

V$zemlin13_11045

1.000/0.894

  

-39 to -17

V$HNF4_01

1.000/0.943

   

V$zemlin13_11045

1.000/0.978

ABCC1

NM_022281.2

-2146 to -2124

V$HNF4_01

1.000/0.908

Mouse

    

ABCB4

NM_008830.2

-5281 to -5259

V$zemlin13_11045

1.000/0.907

ABCC1

NM_008576.2

+2626 to +2648 (Intron 1)

V$HNF4_01

1.000/0.924

   

V$zemlin13_11045

1.000/0.910

  1. Transfac matrix (V$HNF4_01) or self-generated matrix (V$zemlin13_11045) with a setting of core and matrix similarity 0.9 was used.