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Figure 3 | BMC Molecular Biology

Figure 3

From: Identification, characterization and expression of novel Sex Hormone Binding Globulin alternative first exons in the human prostate

Figure 3

Splicing patterns of the SHBG alternative first exons. A) Comparison of the splicing pattern of the exon 1N with the exon 1E (RACEfrag 2) and exon 1D (RACEfrags 3 and 4). Numbers above the exons indicate the nucleotide position in the chromosome 17 of the TSSs (tss) and 3’ends of each exon. B) Diagram showing the 5’end of the SHBG gene. SHBG coding exons are shown as black boxes and alternative and non-coding SHBG first exons as coloured boxes. Arrowheads indicate the different SHBG TSSs. C) Electropherograms of SHBG transcripts showing the exon-exon junctions between the different alternative first exons and exon 2. All transcripts containing different alternative SHBG first exons use the same 3’splice site (3’ss) of exon 2. The consensus 3’splice site of intron 1, the pyrimidine tract (Py) and the potential branch point (BP) are shown.

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