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Figure 2 | BMC Molecular Biology

Figure 2

From: Parental origin of chromosomes influences crossover activity within the Kcnq1 transcriptionally imprinted domain of Mus musculus

Figure 2

Recombination map for the H19-Igf2 and Kcnq1 region of mouse chromosome 7. (A) Coarse recombination mapping across the two transcriptionally imprinted domains (labeled and highlighted by grey bars). Average crossover rate for H19-Igf2 region was 0.14 cM/Mb while the Kcnq1 domain showed a recombination frequency of 2.98 cM/Mb. (B) Comparison of recombination activity between CAST♀xB6♂ and B6♀xCAST♂ parental crosses at an average 172 kb resolution. Only one interval showed significant difference in recombination activity between the reciprocal parental cross (P-value = 0.027, corrected for multiple testing by the Bioufferoni technique).

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BMC Molecular Biology

ISSN: 1471-2199

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