Figure 4From: Human sex hormone-binding globulin gene expression- multiple promoters and complex alternative splicingConfiguration of A) human SHBG exon 1L and B) exon 1T. Transcriptional start sites, as determined in this study, are in bold letters and are denoted by a "≥ ". For both exons, position +1 is assigned to the distal, upstream start site. The exon 1L proximal start site is at position +42, the exon 1T proximal start site is at position +23. Upstream sequences are in italics. Previously reported human transcriptional start sites are underlined; not shown are two additional exon 1L start sites mapped at positions -114 and -125 [22]. Transcriptional start sites mapped in transgenic mice are in lower case letters [23]. "r" and "b" denote the corresponding positions of the major exon 1L rat [43] and rabbit [44] transcriptional start sites, respectively.Back to article page